Vimax Pills Price in Pakistan

Vimax pills Description: 

Vimax is a powerful and natural herbal male enhancement supplement that helps to increase sexual desire and endurance. Formulated from specially selected herbs found around the world, when taken as recommended Vimax has been shown to improve male sexual performance, helping men achieve stronger and longer lasting erections.Make Love Like A Warrior! In Polynesia it has been reported that men of the Mangaian tribe average sexual intercourse three times a night, every single night! Vimax's specially blended herbal formula consists of some of the same type of herbal ingredients regularly used by the Mangaian tribe. While you may not wish to have sex quite as frequently as a Mangaian, it is comforting to know that your sexual performance could improve.Vimax pills are 100% Safe and Natural. Only the highest quality herbal ingredients from around the world are used in the manufacture of Vimax. We are happy to say that our product is used by men aged from 18-78 years old, with no customer reports of side effects. Without our commitment to maintaining the highest standards of product research, development and manufacturing, such powerful results across such a widespread age group would not be possible. Vimax is a powerful and natural herbal male enhancement supplement that helps to increase sexual desire ,improves erectile dysfunction and endurance. 

Why Vimax is #1 Supplement For Men: 

100% Natural and Safe 

Highest Quality Of Herbal Ingredients 

Better Performance and More Satisfaction 

Increase Your Desire and Pleasure 

Improved Endurance 

Weeks 1-4 You may notice a significant increase in sexual desire and stamina 

(as showed by a Vimax Team survey with over 9000 participants). 

Weeks 5-8 You might feel improvement in your performance and satisfaction during sexual intercourse 

(80% of surveyed men report such benefits). 

Weeks 9+ You should reach your full potential by this point. Your partner should also start to 

feel more satisfaction during sexual activity. 

Side Effect: 

No Side Effects reported till date. 

How to use: 

Take 1 pill a day in the morning with water. Also if you wish to enhance your sexual performance 

take 1 pill 30 minutes before sexual activity. 

Price PKR: 3000/ - 

Vimax Price 30 Tablets Pack :- 2999/ - PKR 

Vimax Price 60 Tablets Pack :- 4999/ - PKR 

Special Offer : Buy Vimax Pills 60 Capsules Pack + Vimax Oil Just In :- 6999/ - PKR

Vimax Online Shopping In Pakistan Visit : http://teletopshop.com/health/vimax-pills-pakistan-149.html

Vimac Pills Online Order : 03006079080 / 03216709080

Vimax Pills In Azad kashmir, Bagh, Bhimber, khuiratta, Kotli, Mangla, Mirpur, Muzaffarabad, Plandri, Rawalakot, Punch, Balochistan, Amir Chah, Bazdar,  Bela, Bellpat, Bagh, Burj, Chagai, Chah, Sandan, Chakku, Chaman, Chhatr, Dalbandin, Dera Bugti, Dhana Sar, Diwana, Duki, Dushi, Duzab, Gajar, Gandava, Garhi, Khairo, Garruck, Ghazluna, Girdan, Gulistan, Gwadar, Gwash, Hab Chauki, Hameedabad, Harnai, Hinglaj, Hoshab, Ispikan, Jhal, JhalJhao, Jhatpat, Jiwani, Kalandi, Kalat, Kamararod, Kanak, Kandi, Kanpur, Kapip, Kappar, Karodi, Katuri, Kharan, Khuzdar, Kikki, Kohan, Kohlu, Korak, Lahri, Lasbela, Liari, Loralai, Mach, Mand, Manguchar, Mashki Chah, Maslti, Mastung, Mekhtar, Merui, Mianez, Murgha Kibzai, Musa Khel Bazar, Nagha Kalat, Nal, Naseerabad,  Nauroz Kalat, Nur Gamma, Nushki, Nuttal, Ormara,  Palantuk, Panjgur, Pasni, Piharak,  Pishin, Qamruddin Karez, Qila Abdullah, Qila Ladgasht, Qila Safed, Qila Saifullah, Quetta, Rakhni, Robat Thana, Rodkhan, Saindak, Sanjawi, Saruna, Shabaz Kalat, Shahpur, Sharam Jogizai, Shingar, Shorap, Sibi, Sonmiani, Spezand, Spintangi, Sui, Suntsar, Surab, Thalo, Tump, Turbat, Umarao, pirMahal, Uthal, Vitakri,  Wadh Washap, Wasjuk, Yakmach, Zhob, Federally Administered Northern Areas/FANA, Astor, Baramula, Hunza, Gilgit, Nagar, Skardu, Shangrila, Shandur, Federally Administered Tribal Areas/FATA, Bajaur, Hangu, Malakand, Miram Shah, Mohmand, Khyber, Kurram, North Waziristan, South Waziristan, Wana,  NWFP, Abbottabad, Ayubia, Adezai, Banda Daud Shah, Bannu, Batagram, Birote, Buner, Chakdara, Charsadda, Chitral, Dargai, Darya Khan, Dera Ismail Khan,  Drasan, Drosh, Hangu,  Haripur, Kalam, Karak, Khanaspur, Kohat, Kohistan, Lakki Marwat, Latamber, Lower Dir, Madyan, Malakand, Mansehra, Mardan,  Mastuj, Mongora, Nowshera, Paharpur, Peshawar, Saidu Sharif, Shangla, Sakesar, Swabi, Swat, Tangi, Tank, Thall, Tordher, Upper Dir, Punjab, Ahmedpur East, Ahmed Nager Chatha, Ali Pur, Arifwala, Attock, Basti Malook, Bhagalchur, Bhalwal, Bahawalnagar, Bahawalpur, Bhaipheru, Bhakkar, Burewala, Chailianwala, Chakwal, Chichawatni, Chiniot, Chowk Azam, Chowk Sarwar Shaheed, Daska, Darya Khan, Dera Ghazi Khan, Derawar Fort, Dhaular, Dina City, Dinga, Dipalpur, Faisalabad, Fateh Jang, Gadar, Ghakhar Mandi, Gujranwala, Gujrat, Gujar Khan, Hafiabad, Haroonabad, Hasilpur, Haveli Lakha, Jampur,  Jhang, Jhelum, Kalabagh, Karor Lal Esan, Kasur, Kamalia, Kamokey, Khanewal, Khanpur, Kharian, Khushab, Kot Addu, Jahania, Jalla Araain, Jauharabad, Laar,  Lahore, Lalamusa, Layyah, Lodhran,  Mamoori, Mandi Bahauddin, Makhdoom Aali, Mandi Warburton, Mailsi, Mian Channu, Minawala, Mianwali, Multan, Murree,  Muridke, Muzaffargarh, Narowal, Okara, Renala Khurd, Rajan Pur, Pak Pattan, Panjgur, Pattoki, Pirmahal, Qila Didar Singh, Rabwah, Raiwind, Rajan Pur, Rahim Yar Khan, Rawalpindi, Rohri, Sadiqabad, Safdar Abad – (Dhaban Singh), Sahiwal, Sangla Hill, Samberial, Sarai Alamgir, Sargodha, Shakargarh, Shafqat Shaheed Chowk, Sheikhupura, Sialkot, Sohawa, Sooianwala, Sundar (city), Talagang, Tarbela, Takhtbai, Taxila, Toba Tek Singh, Vehari, Wah Cantonment, Wazirabad, Sindh, Ali Bandar, Baden, Chachro, Dadu, Digri, Diplo, Dokri, Gadra, Ghanian, Ghauspur, Ghotki, Hala, Hyderabad, Islamkot, Jacobabad, Jamesabad, Jamshoro, Janghar, Jati (Mughalbhin), Jhudo, Jungshahi, Kandiaro, Karachi, Kashmor, Keti Bandar, Khairpur, Khora, Klupro, Khokhropur, Korangi, Kotri, Kot Sarae, Larkana, Lund, Mathi, Matiari, Mehar, Mirpur Batoro, Mirpur Khas, Mirpur Sakro, Mithi, Mithani, Moro, Nagar Parkar, Naushara, Naudero, Noushero Feroz, Nawabshah, Nazimabad, Naokot, Pendoo, Pokran, Qambar, Qazi Ahmad, Ranipur, Ratodero, Rohri, Saidu Sharif, Sakrand, Sanghar, Shadadkhot,  Shahbandar, Shahdadpur, Shahpur Chakar, Shikarpur, Sujawal, Sukkur, Tando Adam, Tando Allahyar, Tando Bago, Tar Ahamd Rind, Thatta, Tujal, Umarkot, Veirwaro, Warah

Magic Delay Cream Price in Pakistan

MAGIC DELAY CREAM (IMPORTED FROM GERMANY) Increase sexual stamina and ejaculation timing upto 30 to 45 minutes. Size: 15g Made in: Germany Advantage: Increase sexual stamina and ejaculation timing upto 30 to 45 minutes. 10...

MAGIC DELAY CREAM (IMPORTED FROM GERMANY)

Increase sexual stamina and ejaculation timing upto 30 to 45 minutes.

Size:

15g

Made in: Germany

Advantage:

Increase sexual stamina and ejaculation timing upto 30 to 45 minutes.

100% Original & No side effect.

How to use?    

1.Wash your penis
2.Apply a normal layer on half length of your penis with your finger tips and leave it.
3.Do not massage.
4.Apply 15 minutes before sex.

Price Is : 1999/-PKR

Magic Delay Cream Original Online in Pakistan.

Magic Delay Cream

 

 

 

 

• Health & Well Being

Availability: In stock

MAGIC DELAY CREAM (IMPORTED FROM GERMANY) Increase sexual stamina and ejaculation timing upto 30 to 45 minutes. Size: 15g Made in: Germany Advantage: Increase sexual stamina and ejaculation timing upto 30 to 45 minutes. 10...

Price 1,999

ORDER NOW

Chek Official Site : http://teletopshop.com/health/magic-delay-cream-pakistan-203.html 

Cialis Tablets in Pakistan

1. Name of the medicinal product

CIALIS* 2.5 mg, 5 mg, 10 mg and 20 mg film-coated tablets.

2. Qualitative and quantitative composition

Each 2.5 mg tablet contains 2.5 mg tadalafil.

Excipient with known effect: Each coated tablet contains 87 mg of lactose (as monohydrate).

Each 5 mg tablet contains 5 mg tadalafil.

Excipient with known effect: Each coated tablet contains 121 mg of lactose (as monohydrate).

Each 10 mg tablet contains 10 mg tadalafil.

Excipient with known effect: Each coated tablet contains 170 mg of lactose (as monohydrate).

Each 20 mg tablet contains 20 mg tadalafil.

Excipient with known effect: Each coated tablet contains 233 mg of lactose (as monohydrate).

For the full list of excipients, see section 6.1.

3. Pharmaceutical form

Film-coated tablet (tablet).

The 2.5 mg tablets are light orange-yellow and almond shaped tablets, marked 'C 2 ½' on one side.

The 5 mg tablets are light yellow and almond shaped tablets, marked 'C 5' on one side.

The 10 mg tablets are light yellow and almond shaped tablets, marked 'C 10' on one side.

The 20 mg tablets are yellow and almond shaped tablets, marked 'C 20' on one side.

4. Clinical particulars

4.1 Therapeutic indications

Treatment of erectile dysfunction in adult males.

In order for tadalafil to be effective for the treatment of erectile dysfunction, sexual stimulation is required.

5 mg only: Treatment of the signs and symptoms of benign prostatic hyperplasia in adult males.

CIALIS is not indicated for use by women.

4.2 Posology and method of administration

Posology

Erectile dysfunction in adult Men

In general, the recommended dose is 10 mg taken prior to anticipated sexual activity and with or without food.

In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. It may be taken at least 30 minutes prior to sexual activity.

The maximum dose frequency is once per day.

Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.

In patients who anticipate a frequent use of CIALIS (i.e., at least twice weekly) a once daily regimen with the lowest doses of CIALIS might be considered suitable, based on patient choice and the physician's judgement.

In these patients, the recommended dose is 5mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5mg once a day based on individual tolerability.

The appropriateness of continued use of the daily regimen should be reassessed periodically.

Benign prostatic hyperplasia in adult men (tadalafil 5 mg only)

The recommended dose is 5 mg, taken at approximately the same time every day with or without food. For adult men being treated for both benign prostatic hyperplasia and erectile dysfunction the recommended dose is also 5 mg taken at approximately the same time every day. Patients who are unable to tolerate tadalafil 5 mg for the treatment of benign prostatic hyperplasia should consider an alternative therapy as the efficacy of tadalafil 2.5 mg for the treatment of benign prostatic hyperplasia has not been demonstrated.

Special Populations

Elderly Men

Dose adjustments are not required in elderly patients.

Men with Renal Impairment

Dose adjustments are not required in patients with mild to moderate renal impairment. For patients with severe renal impairment, 10 mg is the maximum recommended dose.

Once-a-day dosing of 2.5 or 5 mg tadalafil both for the treatment of erectile dysfunction or benign prostatic hyperplasia is not recommended in patients with severe renal impairment (see sections 4.4 and 5.2).

Men with Hepatic Impairment

For the treatment of erectile dysfunction using on-demand CIALIS the recommended dose of CIALIS is 10 mg taken prior to anticipated sexual activity and with or without food. There is limited clinical data on the safety of CIALIS in patients with severe hepatic impairment (Child-Pugh class C); if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. There are no available data about the administration of doses higher than 10mg of tadalafil to patients with hepatic impairment.

Once-a-day dosing both for the treatment of erectile dysfunction and benign prostatic hyperplasia has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician (see sections 4.4 and 5.2).

Men with Diabetes

Dose adjustments are not required in diabetic patients.

Paediatric population

There is no relevant use of CIALIS in the paediatric population with regard to the treatment of erectile dysfunction.

Method of administration

CIALIS is available as 2.5, 5, 10, and 20 mg film-coated tablets for oral use.

4.3 Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

In clinical studies, tadalafil was shown to augment the hypotensive effects of nitrates. This is thought to result from the combined effects of nitrates and tadalafil on the nitric oxide/cGMP pathway. Therefore, administration of CIALIS to patients who are using any form of organic nitrate is contraindicated (see section 4.5).

CIALIS must not be used in men with cardiac disease for whom sexual activity is inadvisable. Physicians should consider the potential cardiac risk of sexual activity in patients with pre-existing cardiovascular disease.

The following groups of patients with cardiovascular disease were not included in clinical trials and the use of tadalafil is therefore contraindicated:

- patients with myocardial infarction within the last 90 days,

- patients with unstable angina or angina occurring during sexual intercourse,

- patients with New York Heart Association Class 2 or greater heart failure in the last 6 months,

- patients with uncontrolled arrhythmias, hypotension (<90/50 mm Hg), or uncontrolled hypertension,

- patients with a stroke within the last 6 months.

CIALIS is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure (see section 4.4).

The co-administration of PDE5 inhibitors, including tadalafil, with guanylate cyclase stimulators, such as riociguat, is contraindicated as it may potentially lead to symptomatic hypotension (see section 4.5).

4.4 Special warnings and precautions for use

Before treatment with CIALIS

A medical history and physical examination should be undertaken to diagnose erectile dysfunction or benign prostatic hyperplasia and determine potential underlying causes, before pharmacological treatment is considered.

Prior to initiating any treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity. Tadalafil has vasodilator properties, resulting in mild and transient decreases in blood pressure (see section 5.1) and as such potentiates the hypotensive effect of nitrates (see section 4.3).

The evaluation of erectile dysfunction should include a determination of potential underlying causes and the identification of appropriate treatment following an appropriate medical assessment. It is not known if CIALIS is effective in patients who have undergone pelvic surgery or radical non-nerve-sparing prostatectomy.

Tadalafil 5 mg - Prior to initiating treatment with tadalafil for benign prostatic hyperplasia patients should be examined to rule out the presence of carcinoma of the prostate and carefully assessed for cardiovascular conditions (see section 4.3).

Cardiovascular

Serious cardiovascular events, including myocardial infarction, sudden cardiac death, unstable angina pectoris, ventricular arrhythmia, stroke, transient ischaemic attacks, chest pain, palpitations and tachycardia, have been reported either post marketing and/or in clinical trials. Most of the patients in whom these events have been reported had pre-existing cardiovascular risk factors. However, it is not possible to definitively determine whether these events are related directly to these risk factors, to CIALIS, to sexual activity, or to a combination of these or other factors.

Tadalafil 2.5 mg and 5 mg - In patients receiving concomitant antihypertensive medicinal products, tadalafil may induce a blood pressure decrease. When initiating daily treatment with tadalafil, appropriate clinical considerations should be given to a possible dose adjustment of the antihypertensive therapy.

In patients who are taking alpha1 blockers, concomitant administration of CIALIS may lead to symptomatic hypotension in some patients (see section 4.5). The combination of tadalafil and doxazosin is not recommended.

Vision

Visual defects and cases of NAION have been reported in connection with the intake of CIALIS and other PDE5 inhibitors. Analyses of observational data suggest an increased risk of acute NAION in men with erectile dysfunction following exposure to tadalafil or other PDE5 inhibitors. As this may be relevant for all patients exposed to tadalafil, the patient should be advised that in case of sudden visual defect, he should stop taking CIALIS and consult a physician immediately (see section 4.3).

Decreased or sudden hearing loss

Cases of sudden hearing loss have been reported after the use of tadalafil. Although other risk factors were present in some cases (such as age, diabetes, hypertension and previous hearing loss history) patients should be advised to stop taking tadalafil and seek prompt medical attention in the event of sudden decrease or loss of hearing.

Renal and hepatic impairment (tadalafil 2.5 mg and 5 mg)

Due to increased tadalafil exposure (AUC), limited clinical experience and the lack of ability to influence clearance by dialysis, once-a-day dosing of CIALIS is not recommended in patients with severe renal impairment.

There is limited clinical data on the safety of single-dose administration of CIALIS in patients with severe hepatic insufficiency (Child-Pugh Class C). Once-a-day administration has not been evaluated in patients with hepatic insufficiency. If CIALIS is prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician.

Hepatic impairment (tadalafil 10 mg and 20 mg)

There is limited clinical data on the safety of single-dose administration of CIALIS in patients with severe hepatic insufficiency (Child-Pugh Class C). If CIALIS is prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician.

Priapism and anatomical deformation of the penis

Patients who experience erections lasting 4 hours or more should be instructed to seek immediate medical assistance. If priapism is not treated immediately, penile tissue damage and permanent loss of potency may result.

CIALIS, should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronie's disease) or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia).

Use with CYP3A4 inhibitors

Caution should be exercised when prescribing CIALIS to patients using potent CYP3A4 inhibitors (ritonavir, saquinavir, ketoconazole, itraconazole, and erythromycin), as increased tadalafil exposure (AUC) has been observed if the medicinal products are combined (see section 4.5).

CIALIS and other treatments for erectile dysfunction

The safety and efficacy of combinations of CIALIS and other PDE5 inhibitors or other treatments for erectile dysfunction have not been studied. The patients should be informed not to take CIALIS in such combinations.

Lactose

CIALIS contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.

4.5 Interaction with other medicinal products and other forms of interaction

Interaction studies were conducted with 10 mg and/or 20 mg tadalafil, as indicated below. With regard to those interaction studies where only the 10 mg tadalafil dose was used, clinically relevant interactions at higher doses cannot be completely ruled out.

Effects of Other Substances on Tadalafil

Cytochrome P450 inhibitors

Tadalafil is principally metabolised by CYP3A4. A selective inhibitor of CYP3A4, ketoconazole (200 mg daily), increased tadalafil (10 mg) exposure (AUC) 2-fold and Cmax by 15%, relative to the AUC and Cmax values for tadalafil alone. Ketoconazole (400 mg daily) increased tadalafil (20 mg) exposure (AUC) 4-fold and Cmax by 22%. Ritonavir, a protease inhibitor (200 mg twice daily), which is an inhibitor of CYP3A4, CYP2C9, CYP2C19, and CYP2D6, increased tadalafil (20 mg) exposure (AUC) 2-fold with no change in Cmax. Although specific interactions have not been studied, other protease inhibitors, such as saquinavir, and other CYP3A4 inhibitors, such as erythromycin, clarithromycin, itraconazole, and grapefruit juice, should be co-administered with caution, as they would be expected to increase plasma concentrations of tadalafil (see section 4.4). Consequently, the incidence of the adverse reactions listed in section 4.8 might be increased.

Transporters

The role of transporters (for example, p-glycoprotein) in the disposition of tadalafil is not known. Therefore, there is the potential of drug interactions mediated by inhibition of transporters.

Cytochrome P450 inducers

A CYP3A4 inducer, rifampicin, reduced tadalafil AUC by 88%, relative to the AUC values for tadalafil alone (10 mg). This reduced exposure can be anticipated to decrease the efficacy of tadalafil; the magnitude of decreased efficacy is unknown. Other inducers of CYP3A4, such as phenobarbital, phenytoin, and carbamazepine, may also decrease plasma concentrations of tadalafil.

Effects of Tadalafil on Other Medicinal Products

Nitrates

In clinical studies, tadalafil (5, 10 and 20 mg) was shown to augment the hypotensive effects of nitrates. Therefore, administration of CIALIS to patients who are using any form of organic nitrate is contraindicated (see section 4.3). Based on the results of a clinical study in which 150 subjects receiving daily doses of tadalafil 20 mg for 7 days and 0.4 mg sublingual nitroglycerin at various times, this interaction lasted for more than 24 hours and was no longer detectable when 48 hours had elapsed after the last tadalafil dose. Thus, in a patient prescribed any dose of CIALIS (2.5 mg- 20 mg), where nitrate administration is deemed medically necessary in a life-threatening situation, at least 48 hours should have elapsed after the last dose of CIALIS before nitrate administration is considered. In such circumstances, nitrates should only be administered under close medical supervision with appropriate haemodynamic monitoring.

Anti-hypertensives (including calcium channel blockers)

The co-administration of doxazosin (4 and 8 mg daily) and tadalafil (5 mg daily dose and 20 mg as a single dose) increases the blood pressure-lowering effect of this alpha-blocker in a significant manner. This effect lasts at least twelve hours and may be symptomatic, including syncope. Therefore, this combination is not recommended (see section 4.4).

In interaction studies performed in a limited number of healthy volunteers, these effects were not reported with alfuzosin or tamsulosin. However, caution should be exercised when using tadalafil in patients treated with any alpha-blockers, and notably in the elderly. Treatments should be initiated at minimal dosage and progressively adjusted.

In clinical pharmacology studies, the potential for tadalafil to augment the hypotensive effects of antihypertensive medicinal products was examined. Major classes of antihypertensive medicinal products were studied, including calcium-channel blockers (amlodipine), angiotensin converting enzyme (ACE) inhibitors (enalapril), beta-adrenergic receptor blockers (metoprolol), thiazide diuretics (bendrofluazide), and angiotensin II receptor blockers (various types and doses, alone or in combination with thiazides, calcium-channel blockers, beta-blockers, and/or alpha-blockers). Tadalafil (10 mg, except for studies with angiotensin II receptor blockers and amlodipine in which a 20 mg dose was applied) had no clinically significant interaction with any of these classes. In another clinical pharmacology study, tadalafil (20 mg) was studied in combination with up to 4 classes of antihypertensives. In subjects taking multiple antihypertensives, the ambulatory-blood-pressure changes appeared to relate to the degree of blood pressure control. In this regard, study subjects whose blood pressure was well controlled, the reduction was minimal and similar to that seen in healthy subjects. In study subjects whose blood pressure was not controlled, the reduction was greater, although this reduction was not associated with hypotensive symptoms in the majority of subjects. In patients receiving concomitant antihypertensive medicinal products, tadalafil 20 mg may induce a blood pressure decrease, which (with the exception of alpha-blockers - see above) is, in general, minor and not likely to be clinically relevant. Analysis of Phase 3 clinical trial data showed no difference in adverse events in patients taking tadalafil with or without antihypertensive medicinal products. However, appropriate clinical advice should be given to patients regarding a possible decrease in blood pressure when they are treated with antihypertensive medicinal products.

Riociguat

Preclinical studies showed an additive systemic blood pressure lowering effect when PDE5 inhibitors were combined with riociguat. In clinical studies, riociguat has been shown to augment the hypotensive effects of PDE5 inhibitors. There was no evidence of favourable clinical effect of the combination in the population studied. Concomitant use of riociguat with PDE5 inhibitors, including tadalafil, is contraindicated (see section 4.3).

5- alpha reductase inhibitors

In a clinical trial that compared tadalafil 5 mg coadministered with finasteride 5 mg to placebo plus finasteride 5 mg in the relief of BPH symptoms, no new adverse reactions were identified. However, as a formal drug-drug interaction study evaluating the effects of tadalafil and 5-alpha reductase inhibitors (5-ARIs) has not been performed, caution should be exercised when tadalafil is co-administered with 5-ARIs.

CYP1A2 substrates (e.g. theophylline)

When tadalafil 10 mg was administered with theophylline (a non-selective phosphodiesterase inhibitor) in a clinical pharmacology study, there was no pharmacokinetic interaction. The only pharmacodynamic effect was a small (3.5 bpm) increase in heart rate. Although this effect is minor and was of no clinical significance in this study, it should be considered when co-administering these medicinal products.

Ethinylestradiol and terbutaline

Tadalafil has been demonstrated to produce an increase in the oral bioavailability of ethinylestradiol; a similar increase may be expected with oral administration of terbutaline, although the clinical consequence of this is uncertain.

Alcohol

Alcohol concentrations (mean maximum blood concentration 0.08%) were not affected by co-administration with tadalafil (10 mg or 20 mg). In addition, no changes in tadalafil concentrations were seen 3 hours after co-administration with alcohol. Alcohol was administered in a manner to maximise the rate of alcohol absorption (overnight fast with no food until 2 hours after alcohol). Tadalafil (20 mg) did not augment the mean blood pressure decrease produced by alcohol (0.7 g/kg or approximately 180 ml of 40% alcohol [vodka] in an 80 kg male) but, in some subjects, postural dizziness and orthostatic hypotension were observed. When tadalafil was administered with lower doses of alcohol (0.6 g/kg), hypotension was not observed and dizziness occurred with similar frequency to alcohol alone. The effect of alcohol on cognitive function was not augmented by tadalafil (10 mg).

Cytochrome P450 metabolised medicinal products

Tadalafil is not expected to cause clinically significant inhibition or induction of the clearance of medicinal products metabolised by CYP450 isoforms. Studies have confirmed that tadalafil does not inhibit or induce CYP450 isoforms, including CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 and CYP2C19.

CYP2C9 substrates (e.g. R-warfarin)

Tadalafil (10 mg and 20 mg) had no clinically significant effect on exposure (AUC) to S-warfarin or R-warfarin (CYP2C9 substrate), nor did tadalafil affect changes in prothrombin time induced by warfarin.

Aspirin

Tadalafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by acetylsalicylic acid.

Antidiabetic medicinal products

Specific interaction studies with antidiabetic medicinal products were not conducted.

4.6 Fertility, pregnancy and lactation

CIALIS is not indicated for use by women.

Pregnancy

There are limited data from the use of tadalafil in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3). As a precautionary measure, it is preferable to avoid the use of CIALIS during pregnancy.

Breastfeeding

Available pharmacodynamic/toxicological data in animals have shown excretion of tadalafil in milk. A risk to the suckling child cannot be excluded. CIALIS should not be used during breast feeding.

Fertility

Effects were seen in dogs that might indicate impairment of fertility. Two subsequent clinical studies suggest that this effect is unlikely in humans, although a decrease in sperm concentration was seen in some men (see sections 5.1 and 5.3).

4.7 Effects on ability to drive and use machines

CIALIS has negligible influence on the ability to drive or use machines. Although the frequency of reports of dizziness in placebo and tadalafil arms in clinical trials was similar, patients should be aware of how they react to CIALIS before driving or using machines.

4.8 Undesirable effects

Summary of the safety profile

The most commonly reported adverse reactions in patients taking CIALIS for the treatment of erectile dysfunction or benign prostatic hyperplasia were headache, dyspepsia, back pain and myalgia, in which the incidences increase with increasing dose of CIALIS. The adverse reactions reported were transient, and generally mild or moderate. The majority of headaches reported with CIALIS once-a-day dosing are experienced within the first 10 to 30 days of starting treatment.

Tabulated summary of adverse reactions

The table below lists the adverse reactions observed from spontaneous reporting and in placebo-controlled clinical trials (comprising a total of 8022 patients on CIALIS and 4422 patients on placebo) for on-demand and once-a-day treatment of erectile dysfunction and the once-a-day treatment of benign prostatic hyperplasia.

Spanish Fly sex Drops in Pakistan

Spanish Fly Drops in Pakistan

Spanish Fly Drops Price in Pakistan : 2500/- PKR

Female Viagra in Pakistan - Viagra For Women

If you have low or no sexual desire, if you are not interested in sexual intercourse, if you feel dry while playing with your partner on bed then Spanish Fly Drops are a great gift for females to make their married life more successful healthier and sexy. The Spanish Fly drops is the best medicine in the world for Female Sex enhancing

Make your female Hot And Hunger For Sex in Just 15 Minutesl

Spanish fly sex drops in pakistan go by plane sex drop is no hue no smell, it is can disintegrate into all types of beverages quickly, after woman drink, it is can effect directly, face turn red and rush breath, Sex desire eyes, wholly body goes very hot and she strongly need hardest sex, After taking Spanish Fly sex Drops in Pakistan female wish to make hard sex drive with male. This merchandise has good effect in estrus induction for male and female, help males and females conceive more magnificent sexy know-how.

If a female wish to make hottest love and want to make extreme sex desire then Spanish Fly Sex Drops in Pakistan is the best solution to make her happy. And have a pleasure night. Become a greet partner with great romance and love

Benefits of Female Sex Drops | Benefits Of Spanish Fly Drops

 Just take 15-20 drop and solve them in water, cold drinks or any beverage, you will feel the results in just 15-20 minutes.

· Drops are plane sex drop is no hue no smell.

· Female sex enhancing drops increase the sexual desire.

· It increases lubrication in the vagina.

· After drinking you will see and observe her breath rate is being fast, her face is being reddened, her eyes are looking to be thirsty for sex

· Now she is ready for a stronger harder n longer sex. 

Usage and dosage:

orally take one part each time, without hue or flavor, rapidly soaked up in any wine or drinks.

Notes:

1. Do not take it except in sexy intercourse and children are not allowed to use it. 

2. Only one piece is taken each time. 3. It is not allowed to use spanish fly sex drops in pakistan for inducing young women.

Specification:

It contain a 5ml/piece.

Storage:

Keep it in Shadow and Dry Environment.

Spanish Fly Pro in Pakistan:

Spanish Fly sex drops in pakistan|Female Viagra in Pakistan|Sex Drops for Women in Pakistan|Sex Drops for Women in Lahore|Female Sex Drops in Islamabad|Sex Pills for Females|Women Sex Timing Tablets

Tags & Keywords:

Spanish fly sex drops in pakistan, spanish fly sex drops in lahore, spanish fly sex drops in karachi, female viagra in pakistan, spanish fly sex drops in faisalabad, spanish fly sex drops in rawalpindi, spanish fly sex drops in islamabad, sex drops for women in pakistan, female sex drops in pakistan, women sex drops in pakistan, sex drops for female in pakistan, spanish fly female sex drops in pakistan, spanish fly sex drops in peshawar, spanish fly sex drops in quetta, spanish fly sex drops in multan, spanish fly sex drops in hyderabad, spanish fly sex drops in gujranwala, spanish fly sex drops, spanish fly sex drops in bahawalpur, spanish fly sex drops in abbottabad, spanish fly sex drops in sialkot, spanish fly sex drops in gujrat, women sex drops in lahore, female sex drops in lahore, sex drops for female in lahore

Spanish Fly Drops Price : 2500

NOTE; (ONLY FOR MARRIED COUPLES) 

Sex Enjoyment Drops For Female

Spanish Gold Fly Female Sex Appealing Drops For More Sexual Desire

2 Packs of 5ml

100% Imported -  No Side Effect -

ORDER NOW

Call & SmS 03006079080 / 03216709080
Whatsapp 03006079080

Hom Delivery Available All Over Pakistan.

 Spanish Fly sex Drops Azad kashmir, Bagh, Bhimber, khuiratta, Kotli, Mangla, Mirpur, Muzaffarabad, Plandri, Rawalakot, Punch, Balochistan, Amir Chah, Bazdar,  Bela, Bellpat, Bagh, Burj, Chagai, Chah, Sandan, Chakku, Chaman, Chhatr, Dalbandin, Dera Bugti, Dhana Sar, Diwana, Duki, Dushi, Duzab, Gajar, Gandava, Garhi, Khairo, Garruck, Ghazluna, Girdan, Gulistan, Gwadar, Gwash, Hab Chauki, Hameedabad, Harnai, Hinglaj, Hoshab, Ispikan, Jhal, JhalJhao, Jhatpat, Jiwani, Kalandi, Kalat, Kamararod, Kanak, Kandi, Kanpur, Kapip, Kappar, Karodi, Katuri, Kharan, Khuzdar, Kikki, Kohan, Kohlu, Korak, Lahri, Lasbela, Liari, Loralai, Mach, Mand, Manguchar, Mashki Chah, Maslti, Mastung, Mekhtar, Merui, Mianez, Murgha Kibzai, Musa Khel Bazar, Nagha Kalat, Nal, Naseerabad,  Nauroz Kalat, Nur Gamma, Nushki, Nuttal, Ormara,  Palantuk, Panjgur, Pasni, Piharak,  Pishin, Qamruddin Karez, Qila Abdullah, Qila Ladgasht, Qila Safed, Qila Saifullah, Quetta, Rakhni, Robat Thana, Rodkhan, Saindak, Sanjawi, Saruna, Shabaz Kalat, Shahpur, Sharam Jogizai, Shingar, Shorap, Sibi, Sonmiani, Spezand, Spintangi, Sui, Suntsar, Surab, Thalo, Tump, Turbat, Umarao, pirMahal, Uthal, Vitakri,  Wadh Washap, Wasjuk, Yakmach, Zhob, Federally Administered Northern Areas/FANA, Astor, Baramula, Hunza, Gilgit, Nagar, Skardu, Shangrila, Shandur, Federally Administered Tribal Areas/FATA, Bajaur, Hangu, Malakand, Miram Shah, Mohmand, Khyber, Kurram, North Waziristan, South Waziristan, Wana,  NWFP, Abbottabad, Ayubia, Adezai, Banda Daud Shah, Bannu, Batagram, Birote, Buner, Chakdara, Charsadda, Chitral, Dargai, Darya Khan, Dera Ismail Khan,  Drasan, Drosh, Hangu,  Haripur, Kalam, Karak, Khanaspur, Kohat, Kohistan, Lakki Marwat, Latamber, Lower Dir, Madyan, Malakand, Mansehra, Mardan,  Mastuj, Mongora, Nowshera, Paharpur, Peshawar, Saidu Sharif, Shangla, Sakesar, Swabi, Swat, Tangi, Tank, Thall, Tordher, Upper Dir, Punjab, Ahmedpur East, Ahmed Nager Chatha, Ali Pur, Arifwala, Attock, Basti Malook, Bhagalchur, Bhalwal, Bahawalnagar, Bahawalpur, Bhaipheru, Bhakkar, Burewala, Chailianwala, Chakwal, Chichawatni, Chiniot, Chowk Azam, Chowk Sarwar Shaheed, Daska, Darya Khan, Dera Ghazi Khan, Derawar Fort, Dhaular, Dina City, Dinga, Dipalpur, Faisalabad, Fateh Jang, Gadar, Ghakhar Mandi, Gujranwala, Gujrat, Gujar Khan, Hafiabad, Haroonabad, Hasilpur, Haveli Lakha, Jampur,  Jhang, Jhelum, Kalabagh, Karor Lal Esan, Kasur, Kamalia, Kamokey, Khanewal, Khanpur, Kharian, Khushab, Kot Addu, Jahania, Jalla Araain, Jauharabad, Laar,  Lahore, Lalamusa, Layyah, Lodhran,  Mamoori, Mandi Bahauddin, Makhdoom Aali, Mandi Warburton, Mailsi, Mian Channu, Minawala, Mianwali, Multan, Murree,  Muridke, Muzaffargarh, Narowal, Okara, Renala Khurd, Rajan Pur, Pak Pattan, Panjgur, Pattoki, Pirmahal, Qila Didar Singh, Rabwah, Raiwind, Rajan Pur, Rahim Yar Khan, Rawalpindi, Rohri, Sadiqabad, Safdar Abad – (Dhaban Singh), Sahiwal, Sangla Hill, Samberial, Sarai Alamgir, Sargodha, Shakargarh, Shafqat Shaheed Chowk, Sheikhupura, Sialkot, Sohawa, Sooianwala, Sundar (city), Talagang, Tarbela, Takhtbai, Taxila, Toba Tek Singh, Vehari, Wah Cantonment, Wazirabad, Sindh, Ali Bandar, Baden, Chachro, Dadu, Digri, Diplo, Dokri, Gadra, Ghanian, Ghauspur, Ghotki, Hala, Hyderabad, Islamkot, Jacobabad, Jamesabad, Jamshoro, Janghar, Jati (Mughalbhin), Jhudo, Jungshahi, Kandiaro, Karachi, Kashmor, Keti Bandar, Khairpur, Khora, Klupro, Khokhropur, Korangi, Kotri, Kot Sarae, Larkana, Lund, Mathi, Matiari, Mehar, Mirpur Batoro, Mirpur Khas, Mirpur Sakro, Mithi, Mithani, Moro, Nagar Parkar, Naushara, Naudero, Noushero Feroz, Nawabshah, Nazimabad, Naokot, Pendoo, Pokran, Qambar, Qazi Ahmad, Ranipur, Ratodero, Rohri, Saidu Sharif, Sakrand, Sanghar, Shadadkhot,  Shahbandar, Shahdadpur, Shahpur Chakar, Shikarpur, Sujawal, Sukkur, Tando Adam, Tando Allahyar, Tando Bago, Tar Ahamd Rind, Thatta, Tujal, Umarkot, Veirwaro, Warah